I recommend using the Withdrawal Optimizer to help you determine your best withdrawal strategy, but if you want to study the effect yourself you can certainly do that using AUTOMATIC DEPOSITS/WITHDRAWALS.
You can have entries for the registered accounts you want to withdraw from, specifying a yearly amount or a yearly % of the account balance, for any date range. The withdrawals will be made in the TIME MACHINE and will contribute to the required minimum withdrawal if one is required. It may not be made (or not in full) if there is a maximum withdrawal limit (like for some LIFs). What is withdrawn ends up in your Wallet.
You can also specify entries for automatic deposits to TFSAs or Non-registered accounts of your choosing. You can match the date ranges and amounts you set for the withdrawals you set on the account above. However, if you set the withdrawal as % of the account balance, you will not know what that amount will be exactly. For TFSAs, the TM will never go over the contribution room whatever you set. The funds for the deposits will come from your Wallet and so should use up the withdrawals you set up.
You can also set up SCANS so you can run multiple scenarios at once. In this case, you could put a scan on the amounts you have set for those automating savings/withdrawals to cover a range. The table of results for the scan will show you the legacy and total taxes paid so you can easily identify the best values to use.